We recommend you check with your prescribing health care practitioner before using The Cleanse while taking your medication. Your health care practitioner should monitor medication for your needs for medication can change during a Cleanse. You may take your normal daily supplements except when on our deepest phase. If you decide to take your daily supplement, it is best to avoid supplements that are protein based, that contain salt, soy, dairy or foods listed on the acid-forming foods list. It is also best to avoid probiotics that contain large amounts of lactobacillus, which is extremely acid-forming. You can however, take our Flora Grow, which contains strains natural to the human body and will not produce an acid environment.